Regimen on Dnaja3 haploinsufficiency mediated sarcopenic obesity with imbalanced mitochondrial homeostasis and lipid metabolism

• Main Authors: Yu‐Ning Fann (Author), Wan‐Huai Teo (Author), Hsin‐Chen Lee (Author), Chen‐Chung Liao (Author), Yeou‐Guang Tsay (Author), Tung‐Fu Huang (Author), Jeng‐Fan Lo (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sarcopenic obesity is characterized by excess fat mass and diminished muscular mass/function. DNAJA3, a mitochondrial co‐chaperone protein, plays a crucial role in skeletal muscle development. GMI, an immunomodulatory protein, promotes myogenic differentiation through DNAJA3 acti...