FFAR4 (GPR120) Signaling Is Not Required for Anti-Inflammatory and Insulin-Sensitizing Effects of Omega-3 Fatty Acids

• Main Authors: Simone Isling Pærregaard (Author), Marianne Agerholm (Author), Annette Karen Serup (Author), Tao Ma (Author), Bente Kiens (Author), Lise Madsen (Author), Karsten Kristiansen (Author), Benjamin Anderschou Holbech Jensen (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Free fatty acid receptor-4 (FFAR4), also known as GPR120, has been reported to mediate the beneficial effects of omega-3 polyunsaturated fatty acids (ω3-PUFAs) by inducing an anti-inflammatory immune response. Thus, activation of FFAR4 has been reported to ameliorate chronic low-grade inflammation a...