Closed-loop neural stimulation for pentylenetetrazole-induced seizures in zebrafish

• Main Authors: Ricardo Pineda (Author), Christine E. Beattie (Author), Charles W. Hall (Author)
• 格式: 图书
• 出版: The Company of Biologists, 2013-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

SUMMARY Neural stimulation can reduce the frequency of seizures in persons with epilepsy, but rates of seizure-free outcome are low. Vagus nerve stimulation prevents seizures by continuously activating noradrenergic projections from the brainstem to the cortex. Cortical norepinephrine then increases...