Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity

• প্রধান লেখক: Huan-yu Guan (লেখক), Peng-fei Li (লেখক), Xiao-ming Wang (লেখক), Jia-jing Yue (লেখক), Yang He (লেখক), Xiao-mei Luo (লেখক), Mei-feng Su (লেখক), Shang-gao Liao (লেখক), Yue Shi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Shengjiang Xiexin decoction (SXD), a classic traditional Chinese medical formula chronicled in Shang Han Lun, is used in modern clinical practice to decrease gastrointestinal toxicity induced by the chemotherapeutic drug irinotecan (CPT-11). In this study, the effect of SXD on the pharmacokinetics o...