In-situ formed thermosensitive hydrogel amplifies statin-mediated immune checkpoint blockade for coordinated tumor chemo-immunotherapy

Small molecule drugs are the next-generation of immune checkpoint inhibitors (ICIs), but their in vivo therapeutic outcomes remain unsatisfactory for a long time. Herein, we proposed a combinatory regimen that delivered a small molecule ICI and an immunogenic cell death inducer in an in-situ formed...

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Main Authors: Zefan Liu (Author), Yajun Zhang (Author), Jinyu Huang (Author), Yan Wang (Author), Xin Kang (Author)
Format: Book
Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
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