Preterm Infant with Generalized Arterial Calcification of Infancy Who Survived Due to Early Diagnosis and Appropriate Treatment with Bisphosphonates: A Case Report

• Main Authors: Masato Tanaka (Author), Akira Kobayashi (Author), Haruhiro Kuwabara (Author), Jun Nirei (Author), Junichi Ozawa (Author), Kentaro Sawano (Author), Nao Shibata (Author), Keisuke Nagasaki (Author), Akihiko Saitoh (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Generalized arterial calcification of infancy (GACI) is a rare disease characterized by arterial calcification. GACI is caused by a mutation in the ENPP1 or ABCC6 genes. GACI causes severe hypertension and heart failure, and approximately 50% of patients die within the first 6 months. In particular,...