Discovery of coumaric acid derivatives hinted by coastal marine source to seek for uric acid lowering agents

• প্রধান লেখক: Yu-Shun Yang (লেখক), Bin Wang (লেখক), Junzhong Liu (লেখক), Qin Li (লেখক), Qin-Cai Jiao (লেখক), Pei Qin (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

In this work, a series of novel compounds Spartinin C1-C24 were screened, synthesised and evaluated for inhibiting xanthine oxidase thus lowering serum uric acid level. The backbones were derived from the components of coastal marine source Spartina alterniflora and marketed drugs. The top hits Spar...