Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients

• Main Authors: Juji Takuo (Author), Mori Toshihito (Author), Yamane Noriko (Author), Shiobara Noriyuki (Author), Tanaka Konagi (Author), Masuda Riako (Author), Kumagai Ken-ichi (Author), Hanamoto Yukie (Author), Ishida Satoru (Author), Yamane Shoji (Author), Fukui Naoshi (Author), Itoh Tsunetoshi (Author), Ochi Takahiro (Author), Suzuki Ryuji (Author)
• Format: Book
• Published: BMC, 2008-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The epidermal growth factor (EGF) and EGF receptor (EGFR) families play important roles in the hyperplastic growth of several tissues as well as tumor growth. Since synovial hyperplasia in rheumatoid arthritis (RA) resembles a tumor,...