Association of CYP3A4*1B, CYP3A4*22 and CYP3A5*3 polymorphisms carriage with efficacy and safety of tamsulosin in patients with benign prostatic hyperplasia

Association of CYP3A4*1B, CYP3A4*22 and CYP3A5*3 polymorphisms carriage with efficacy and safety of tamsulosin in patients with benign prostatic hyperplasia

Tamsulosin is a first-line drug in the treatment of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH). Despite high estimates of its efficacy and safety, it rates may vary due to genetic polymorphisms of genes for the enzymes involved in the drugs metabolism.The aim of the wo...

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Main Authors: Sh. P. Abdullaev (Author), M. N. Shatokhin (Author), O. L. Sigailo (Author), P. O. Bochkov (Author), S. N. Tuchkova (Author), O. V. Teodorovich (Author), O. B. Loran (Author), D. A. Sychev (Author)
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Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute, 2024-05-01T00:00:00Z.
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