Clinical manifestations, toxicities, and outcome of two children with Nijmegen breakage syndrome and lymphoid malignancies - case reports

• Main Authors: Aleksandra Filipiuk (Author), Agata Kozakiewicz (Author), Kamil Kośmider (Author), Katarzyna Karska (Author), Monika Lejman (Author), Joanna Zawitkowska (Author)
• Format: Book
• Published: Termedia Publishing House, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nijmegen breakage syndrome (NBS) is a rare disease with an autosomal recessive pattern of inheritance caused by mutations in the NBN gene. We report 2 patients with NBS and T-cell lymphoblastic lymphoma (T-LBL), in whom diagnosis and therapy were difficult challenges. Both patients were diagnosed wi...