Effect of Poloxamer on release of poorly water soluble drug Loratadine from solid dispersion: Kneading method

• Những tác giả chính: M. Mofizur Rahman (Tác giả), Mohammad Moniruzzaman (Tác giả), Sanjida Haque (Tác giả), M.A.K. Azad (Tác giả), Farjana Islam Aovi (Tác giả), Nazneen Ahmeda Sultana (Tác giả)
• Định dạng: Sách
• Được phát hành: University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association, 2015-05-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

The main objective of the current study was to enhance the solubility and dissolution of poorly water soluble drug Loratadine (LOR) through formulation of solid dispersion systems (SDs) using hydrophilic polymers. SDs were prepared by kneading method using different drug-to-polymer ratios (1:3 and 1...