Puerarin prevents progression of experimental hypoxia-induced pulmonary hypertension via inhibition of autophagy

• Main Authors: Xiaodan Zhang (Author), Qi Liu (Author), Chen Zhang (Author), Jiejing Sheng (Author), Songlin Li (Author), Wendi Li (Author), Xinying Yang (Author), Xiaoying Wang (Author), Siyu He (Author), June Bai (Author), Daling Zhu (Author)
• Format: Book
• Published: Elsevier, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary arterial hypertension (PAH) is defined as elevation of mean pulmonary arterial pressure to ≥25 mmHg within the low pressure pulmonary circulatory system. PAH is characterized by obstructive vascular remodeling, partially due to excessive pulmonary arterial smooth muscle cell (PASMC) prolif...