Sinensetin protects against periodontitis through binding to Bach1 enhancing its ubiquitination degradation and improving oxidative stress

• Main Authors: Zhiyao Yuan (Author), Junjie Li (Author), Fuyu Xiao (Author), Yu Wu (Author), Zhiting Zhang (Author), Jiahong Shi (Author), Jun Qian (Author), Xudong Wu (Author), Fuhua Yan (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible patients is often unsatisfactory due to excessive inflammatory response and oxidative stress. Sinensetin (Sin) is a nature polymethoxylated flavonoi...