Impact of DNA double-strand breaks on pancreaticobiliary maljunction carcinogenesis

• Main Authors: Yasuhiro Kuraishi (Author), Takeshi Uehara (Author), Takashi Muraki (Author), Mai Iwaya (Author), Yasuhiro Kinugawa (Author), Tomoyuki Nakajima (Author), Takayuki Watanabe (Author), Yusuke Miyagawa (Author), Takeji Umemura (Author)
• Format: Book
• Published: BMC, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pancreaticobiliary maljunction (PBM) is a condition characterized by chronic inflammation due to refluxed pancreatic juice into the biliary tract that is associated with an elevated risk of biliary tract cancer. DNA double-strand breaks (DSBs) are considered the most serious form...