Central precocious puberty with hypothalamic hamartoma: the first case reports of 2 siblings with different phenotypes of Seckel syndrome 5

• Main Authors: Jisun Park (Author), Minjun Jeon (Author), Seri Maeng (Author), Dae Kyu Kwon (Author), Sujin Kim (Author), Ji Eun Lee (Author)
• Format: Book
• Published: Korean Society of Pediatric Endocrinology, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypothalamic hamartomas (HHs) are nonneoplastic mass lesions located in the hypothalamus that can cause central precocious puberty (CPP) and/or gelastic seizures. Seckel syndrome 5 (OMIM210600, SCKL5) is a rare autosomal recessive genetic spectrum disorder characterized by intrauterine growth retard...