Steroidogenic control of liver metabolism through a nuclear receptor-network

• Main Authors: Alexandra Milona (Author), Vittoria Massafra (Author), Harmjan Vos (Author), Jyoti Naik (Author), Natalia Artigas (Author), Helen A.B. Paterson (Author), Ingrid T.G.W. Bijsmans (Author), Ellen C.L. Willemsen (Author), Jose M. Ramos Pittol (Author), Irene Miguel-Aliaga (Author), Piter Bosma (Author), Boudewijn M.T. Burgering (Author), Catherine Williamson (Author), Santiago Vernia (Author), Waljit S. Dhillo (Author), Saskia W.C. van Mil (Author), Bryn M. Owen (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Coupling metabolic and reproductive pathways is essential for the survival of species. However, the functions of steroidogenic enzymes expressed in metabolic tissues are largely unknown. Methods and results: Here, we show that in the liver, the classical steroidogenic enzyme Cyp17a1 forms...