Multivariate Analytical Approaches to Identify Key Molecular Properties of Vehicles, Permeants and Membranes That Affect Permeation through Membranes

• Main Authors: Omaima N. Najib (Author), Stewart B. Kirton (Author), Gary P. Martin (Author), Michelle J. Botha (Author), Al-Sayed Sallam (Author), Darragh Murnane (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There has been considerable recent interest in employing computer models to investigate the relationship between the structure of a molecule and its dermal penetration. Molecular permeation across the epidermis has previously been demonstrated to be determined by a number of physicochemical properti...