Impact of SARS-CoV-2 Mutations on PCR Assay Sequence Alignment

• Главные авторы: Daniel Antonio Negrón (Автор), June Kang (Автор), Shane Mitchell (Автор), Mitchell Y. Holland (Автор), Stephen Wist (Автор), Jameson Voss (Автор), Lauren Brinkac (Автор), Katharine Jennings (Автор), Stephanie Guertin (Автор), Bruce G. Goodwin (Автор), Shanmuga Sozhamannan (Автор)
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• Опубликовано: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Предметы: article
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Real-time reverse transcription polymerase chain reaction (RT-PCR) assays are the most widely used molecular tests for the detection of SARS-CoV-2 and diagnosis of COVID-19 in clinical samples. PCR assays target unique genomic RNA regions to identify SARS-CoV-2 with high sensitivity and specificity....