Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model

• Main Authors: James Phie (Author), Shivshankar Thanigaimani (Author), Pacific Huynh (Author), Raghuveeran Anbalagan (Author), Corey S. Moran (Author), Robert Kinobe (Author), Joseph V. Moxon (Author), Matt A. Field (Author), Smriti M. Krishna (Author), Jonathan Golledge (Author)
• Format: Book
• Published: Hindawi-Wiley, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aims. The nacht domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome is upregulated in human abdominal aortic aneurysm (AAA), but its pathogenic role is unclear. The aims of this study were firstly to examine whether the inflammasome was upregulated...