Suramin Affects the Renal VEGF-A/VEGFR Axis in Short-Term Streptozotocin-Induced Diabetes

• मुख्य लेखकों: Gabriela Chyła-Danił (लेखक), Kornelia Sałaga-Zaleska (लेखक), Ewelina Kreft (लेखक), Aleksandra Krzesińska (लेखक), Sylwia Herman (लेखक), Agnieszka Kuchta (लेखक), Monika Sakowicz-Burkiewicz (लेखक), Małgorzata Lenartowicz (लेखक), Maciej Jankowski (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Diabetic nephropathy (DN) accounts for approximately 50% of end-stage renal diseases. Vascular endothelial growth factor A (VEGF-A) is thought to be a critical mediator of vascular dysfunction in DN, but its role is unclear. The lack of pharmacological tools to modify renal concentrations further hi...