Coordinated regulation of BACH1 and mitochondrial metabolism through tumor-targeted self-assembled nanoparticles for effective triple negative breast cancer combination therapy

• Egile Nagusiak: Xuan Yang (Egilea), Yalong Wang (Egilea), Junke Zhao (Egilea), Hehui Rong (Egilea), Yujun Chen (Egilea), Mengting Xiong (Egilea), Xiaoxing Ye (Egilea), Shihui Yu (Egilea), Haiyan Hu (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2022-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The poor prognosis of triple negative breast cancer (TNBC) results from a lack of approved targeted therapies coupled with aggressive proliferation and metastasis, which is associated with high recurrence and short overall survival. Here we developed a strategy by employing tumor-targeted self-assem...