Coordinated regulation of BACH1 and mitochondrial metabolism through tumor-targeted self-assembled nanoparticles for effective triple negative breast cancer combination therapy

• Main Authors: Xuan Yang (Author), Yalong Wang (Author), Junke Zhao (Author), Hehui Rong (Author), Yujun Chen (Author), Mengting Xiong (Author), Xiaoxing Ye (Author), Shihui Yu (Author), Haiyan Hu (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The poor prognosis of triple negative breast cancer (TNBC) results from a lack of approved targeted therapies coupled with aggressive proliferation and metastasis, which is associated with high recurrence and short overall survival. Here we developed a strategy by employing tumor-targeted self-assem...