An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides

• Main Authors: Cleopatra Kozlowski (Author), Surinder Jeet (Author), Joseph Beyer (Author), Steve Guerrero (Author), Justin Lesch (Author), Xiaoting Wang (Author), Jason DeVoss (Author), Lauri Diehl (Author)
• Format: Book
• Published: The Company of Biologists, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY The DSS (dextran sulfate sodium) model of colitis is a mouse model of inflammatory bowel disease. Microscopic symptoms include loss of crypt cells from the gut lining and infiltration of inflammatory cells into the colon. An experienced pathologist requires several hours per study to score h...