Population PK/PD modelling of meropenem in preterm newborns based on therapeutic drug monitoring data

• Main Authors: Sergey Zyryanov (Author), Irina Bondareva (Author), Olga Butranova (Author), Alexandra Kazanova (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Background: Preterm neonates rarely participate in clinical trials, this leads to lack of adequate information on pharmacokinetics for most drugs in this population. Meropenem is used in neonates to treat severe infections, and absence of evidence-based rationale for optimal dosing could result in m...