Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid.

• Главные авторы: Rodrigo Frezzatti (Автор), Paulo Flavio Silveira (Автор)
• Формат: ‌
• Опубликовано: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Предметы: article
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BACKGROUND: Acute renal failure is one of the most serious complications of envenoming resulting from Crotalus durissus terrificus bites. This study evaluated the relevance of hyperuricemia and oxidative stress and the effects of allopurinol and probenecid in renal dysfunction caused by direct nephr...