PEP06 polypeptide 30 is a novel cluster-dissociating agent inhibiting αv integrin/FAK/Src signaling in oral squamous cell carcinoma cells

• Main Authors: Gulnara Tuguzbaeva (Author), Er Yue (Author), Xi Chen (Author), Lina He (Author), Xinlei Li (Author), Jiaming Ju (Author), Ying Qin (Author), Valentin Pavlov (Author), Yanjie Lu (Author), Wenting Jia (Author), Yunlong Bai (Author), Yumei Niu (Author), Baofeng Yang (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Collectively migrating tumor cells have been recently implicated in enhanced metastasis of epithelial malignancies. In oral squamous cell carcinoma (OSCC), αv integrin is a crucial mediator of multicellular clustering and collective movement in vitro; however, its contribution to metastatic spread r...