A novel Glycyrrhiza glabra extract liquiritin targeting NFATc1 activity and ROS levels to counteract ovariectomy-induced osteoporosis and bone loss in murine model

• Autors principals: Guoju Hong (Autor), Lin Zhou (Autor), Guanqiang Zheng (Autor), Xiaoxia Zheng (Autor), Zhenqiu Chen (Autor), Wei He (Autor), Qiushi Wei (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Osteoporosis, a prevalent osteolytic condition worldwide, necessitates effective strategies to inhibit excessive bone resorption by curbing osteoclast hyperactivation. Liquiritin (LIQ), an flavanone derivative employed in acute lung injury and rheumatoid arthritis treatment, possesses an unclear rol...