PEGylated Chitosan Nanoparticles Encapsulating Ascorbic Acid and Oxaliplatin Exhibit Dramatic Apoptotic Effects against Breast Cancer Cells

PEGylated Chitosan Nanoparticles Encapsulating Ascorbic Acid and Oxaliplatin Exhibit Dramatic Apoptotic Effects against Breast Cancer Cells

This study aims to design a pH-responsive dual-loaded nanosystem based on PEGylated chitosan nanoparticles loaded with ascorbic acid (AA) and oxaliplatin (OX) for the effective treatment of breast cancer. In this regard, non-PEGylated and PEGylated chitosan nanoparticles (CS NPs) loaded with either...

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Main Authors: Sherif Ashraf Fahmy (Author), Asmaa Ramzy (Author), Asmaa A. Mandour (Author), Soad Nasr (Author), Anwar Abdelnaser (Author), Udo Bakowsky (Author), Hassan Mohamed El-Said Azzazy (Author)
Format: Book
Published: MDPI AG, 2022-02-01T00:00:00Z.
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