Optimizing Aggregated N-Of-1 Trial Designs for Predictive Biomarker Validation: Statistical Methods and Theoretical Findings

Background and Significance: Parallel-group randomized controlled trials (PG-RCTs) are the gold standard for detecting differences in mean improvement across treatment conditions. However, PG-RCTs provide limited information about individuals, making them poorly optimized for quantifying the relatio...

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Bibliographic Details
Main Authors: Rebecca C. Hendrickson (Author), Ronald G. Thomas (Author), Nicholas J. Schork (Author), Murray A. Raskind (Author)
Format: Book
Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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