(+)-Panduratin A induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway

Background: Human pancreatic cancer cells have an extreme tolerance to nutrition starvation, enabling them to survive in the hypovascular tumor microenvironment, a phenomenon also known as "austerity". Discovery of agents that preferentially inhibit cancer cells' tolerance to nutritio...

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Main Authors: Sijia Sun (Author), Min Jo Kim (Author), Ashraf M. Omar (Author), Nguyen Duy Phan (Author), Suresh Awale (Author)
Format: Book
Published: Elsevier, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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