(+)-Panduratin A induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway

• প্রধান লেখক: Sijia Sun (লেখক), Min Jo Kim (লেখক), Ashraf M. Omar (লেখক), Nguyen Duy Phan (লেখক), Suresh Awale (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2021-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Human pancreatic cancer cells have an extreme tolerance to nutrition starvation, enabling them to survive in the hypovascular tumor microenvironment, a phenomenon also known as "austerity". Discovery of agents that preferentially inhibit cancer cells' tolerance to nutritio...