Expression of erythropoietin and its receptor increases in colonic neoplastic progression: The role of hypoxia in tumorigenesis

• Hlavní autoři: Zoltan Gombos (Autor), Ludovit Danihel (Autor), Vanda Repiska (Autor), Geza Acs (Autor), Emma Furth (Autor)
• Médium: Kniha
• Vydáno: Wolters Kluwer Medknow Publications, 2011-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Background: Tissue hypoxia is a characteristic patho-physiologic property of colorectal cancer. This process may also add to a therapeutic problem of solid tumor resistance to chemo- and radiation therapy. Erythropoietin (Epo) expression is induced by tissue hypoxia. Acting via its receptor (EpoR),...