Esomeprazole Increases Airway Surface Liquid pH in Primary Cystic Fibrosis Epithelial Cells

• المؤلفون الرئيسيون: Livia Delpiano (مؤلف), Joseph J. Thomas (مؤلف), Annabel R. Yates (مؤلف), Sarah J. Rice (مؤلف), Michael A. Gray (مؤلف), Vinciane Saint-Criq (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Respiratory failure, driven by airways mucus obstruction, chronic inflammation and bacterial infections, is the main cause of mortality and morbidity in people with cystic fibrosis (CF) due to defects in the Cl- and HCO3− transport activity of the CF Transmembrane conductance Regulator (CFTR). Most...