Synthesis of cyclo-L-prolyl-glycine and study of its anti-parkinsonian activity

• Main Authors: Ksenia Koliasnikova (Author), Anna Golubyatnikova (Author), Alexey Rebeko (Author), Marina Vukolova (Author), Polina Povarnina (Author), Elena Kuznetsova (Author)
• פורמט: ספר
• יצא לאור: LLC "Publisher OKI", 2019-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The aim of the work was to develop an optimal scheme for the synthesis of substance of cyclo-L-prolylglycine neuropeptide (CPG), a potential drug useful for the integrated treatment of psychiatric pathologies, including anxiety, depressive disorders and cognitive impairment. Two 4-stage CPG synthesi...