Personalizing Colon Cancer Therapeutics: Targeting Old and New Mechanisms of Action

The use of pharmaceuticals for colon cancer treatment has been increasingly personalized, in part due to the development of new molecular tools. In this review, we discuss the old and new colon cancer chemotherapeutics, and the parameters that have been shown to be predictive of efficacy and safety...

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Bibliographic Details
Main Authors: Wafik S. El-Deiry (Author), Christina Leah B. Kline (Author)
Format: Book
Published: MDPI AG, 2013-08-01T00:00:00Z.
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Summary:The use of pharmaceuticals for colon cancer treatment has been increasingly personalized, in part due to the development of new molecular tools. In this review, we discuss the old and new colon cancer chemotherapeutics, and the parameters that have been shown to be predictive of efficacy and safety of these chemotherapeutics. In addition, we discuss how alternate pharmaceuticals have been developed in light of a potential lack of response or resistance to a particular chemotherapeutic.
Item Description:10.3390/ph6080988
1424-8247