Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics

• Main Authors: Alexander J. Plant-Hately (Author), Burcu Eryilmaz (Author), Christopher A. W. David (Author), Danielle E. Brain (Author), Bethany J. Heaton (Author), Yvonne Perrie (Author), Neill J. Liptrott (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipidic nanoparticles (LNP), particularly liposomes, have been proven to be a successful and versatile platform for intracellular drug delivery for decades. Whilst primarily developed for small molecule delivery, liposomes have recently undergone a renaissance due to their success in vaccination str...