A Comparative Study of Cluster Detection Algorithms in Protein-Protein Interaction for Drug Target Discovery and Drug Repurposing

• Main Authors: Jun Ma (Author), Jenny Wang (Author), Laleh Soltan Ghoraie (Author), Xin Men (Author), Benjamin Haibe-Kains (Author), Penggao Dai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The interactions between drugs and their target proteins induce altered expression of genes involved in complex intracellular networks. The properties of these functional network modules are critical for the identification of drug targets, for drug repurposing, and for understanding the underlying m...