Effects of zoledronic acid on osteoblasts in three-dimensional culture

• Main Authors: Flora Thibaut (Author), Tanguy Watrin (Author), Fleur Meary (Author), Sylvie Tricot (Author), Virginie Legros (Author), Pascal Pellen-Mussi (Author), Dominique Chauvel-Lebret (Author)
• Format: Book
• Published: Elsevier, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Bisphosphonates (BPs) are synthetic drugs with antitumor and bone antiresorptive activities. The use of BPs is suspected to favor the emergence of osteonecrosis of the jaw (ONJ), a putative side effect whose pathogenesis remains unclear. Thus, we aimed to get insights about the i...