Population and Noncompartmental Pharmacokinetics of Sodium Oxybate Support Weight‐Based Dosing in Children and Adolescents With Narcolepsy With Cataplexy

• Hoofdauteurs: Cuiping Chen (Auteur), Carol L. Rosen (Auteur), Chad Ruoff (Auteur), Leslie H. Boyce (Auteur), Rupa Parvataneni (Auteur), Katie Zomorodi (Auteur), Scott Brantley (Auteur), Mark Sale (Auteur), Giuseppe Plazzi (Auteur)
• Formaat: Boek
• Gepubliceerd in: Wiley, 2020-09-01T00:00:00Z.
• Onderwerpen: article
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The pharmacokinetics (PKs) of sodium oxybate (SXB) was evaluated in a subset of participants from a study of SXB treatment in children (aged 7-11 years; n = 11) and adolescents (aged 12-17 years; n = 18) with narcolepsy with cataplexy. PK evaluation was conducted over 2 nights during the period when...