Population and Noncompartmental Pharmacokinetics of Sodium Oxybate Support Weight‐Based Dosing in Children and Adolescents With Narcolepsy With Cataplexy

• Main Authors: Cuiping Chen (Author), Carol L. Rosen (Author), Chad Ruoff (Author), Leslie H. Boyce (Author), Rupa Parvataneni (Author), Katie Zomorodi (Author), Scott Brantley (Author), Mark Sale (Author), Giuseppe Plazzi (Author)
• 格式: 图书
• 出版: Wiley, 2020-09-01T00:00:00Z.
• 主题: article
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The pharmacokinetics (PKs) of sodium oxybate (SXB) was evaluated in a subset of participants from a study of SXB treatment in children (aged 7-11 years; n = 11) and adolescents (aged 12-17 years; n = 18) with narcolepsy with cataplexy. PK evaluation was conducted over 2 nights during the period when...