The Causative Pathogen Determines the Inflammatory Profile in Cerebrospinal Fluid and Outcome in Patients with Bacterial Meningitis

• Main Authors: Denis Grandgirard (Author), Rahel Gäumann (Author), Boubacar Coulibaly (Author), Jean-Pierre Dangy (Author), Ali Sie (Author), Thomas Junghanss (Author), Hans Schudel (Author), Gerd Pluschke (Author), Stephen L. Leib (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The brain's inflammatory response to the infecting pathogen determines the outcome of bacterial meningitis (BM), for example, the associated mortality and the extent of brain injury. The inflammatory cascade is initiated by the presence of bacteria in the cerebrospinal fluid (CSF) a...