NAG-1/GDF15 Transgenic Mouse Has Less White Adipose Tissue and a Reduced Inflammatory Response

• Главные авторы: J. M. Kim (Автор), J. P. Kosak (Автор), J. K. Kim (Автор), G. Kissling (Автор), D. R. Germolec (Автор), D. C. Zeldin (Автор), J. A. Bradbury (Автор), S. J. Baek (Автор), T. E. Eling (Автор)
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• Опубликовано: Hindawi Limited, 2013-01-01T00:00:00Z.
• Предметы: article
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NAG-1/GDF15 is a TGF-β superfamily member with poorly characterized biological activity proposed to inhibit inflammatory cytokine production. Transgenic mice expressing human NAG-1/GDF15 (NAG-1Tg/Lox) are leaner with lower body weight and are resistant to chemically or genetically induced intestinal...