Usefulness and difficulties with the thiopurine pharmacogenomic NUDT15 genotyping test: Analysis of real-world data in Japan

• Prif Awduron: Yoichi Kakuta (Awdur), Motohiro Kato (Awdur), Yusuke Shimoyama (Awdur), Takeo Naito (Awdur), Rintaro Moroi (Awdur), Masatake Kuroha (Awdur), Hisashi Shiga (Awdur), Yoshitaka Kinouchi (Awdur), Atsushi Masamune (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2023-11-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The usefulness of NUDT15 genotyping as a pharmacogenomic test for thiopurine has been established. The first such test developed to date, NUDT15 genotyping was approved for reimbursement in Japan in February 2019 for all indicated patients. We retrospectively examined claims data in Japan and confir...