Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles.

• Main Authors: Sunamita de Carvalho Lima (Author), Lucas de Carvalho Porta (Author), Álvaro da Costa Lima (Author), Joana D'Arc Campeiro (Author), Ywlliane Meurer (Author), Nathália Bernardes Teixeira (Author), Thiago Duarte (Author), Eduardo Brandt Oliveira (Author), Gisele Picolo (Author), Rosely Oliveira Godinho (Author), Regina Helena Silva (Author), Mirian Akemi Furuie Hayashi (Author)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2018-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The high medical importance of Crotalus snakes is unquestionable, as this genus is the second in frequency of ophidian accidents in many countries, including Brazil. With a relative less complex composition compared to other genera venoms, as those from the Bothrops genus, the Crotalus genus venom f...