Identification of novel mutation in cathepsin C gene causing Papillon-Lefèvre Syndrome in Mexican patients

• Main Authors: Romero-Quintana José G (Author), Frías-Castro Luis O (Author), Arámbula-Meraz Eliakym (Author), Aguilar-Medina Maribel (Author), Dueñas-Arias Jesús E (Author), Melchor-Soto Jesús D (Author), Romero-Navarro José G (Author), Ramos-Payán Rosalío (Author)
• Format: Book
• Published: BMC, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Papillon-Lefèvre Syndrome (PLS) is a type IV genodermatosis caused by mutations in cathepsin C (CTSC), with a worldwide prevalence of 1-4 cases per million in the general population. In México, the prevalence of this syndrome is un...