Efficacies and ADME properties of redox active methylene blue and phenoxazine analogues for use in new antimalarial triple drug combinations with amino-artemisinins

• Main Authors: Daniel J. Watson (Author), Lizahn Laing (Author), Jacobus P. Petzer (Author), Ho Ning Wong (Author), Christopher J. Parkinson (Author), Lubbe Wiesner (Author), Richard K. Haynes (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Efforts to develop new artemisinin triple combination therapies effective against artemisinin-tolerant strains of Plasmodium falciparum based on rational combinations comprising artemisone or other amino-artemisinins, a redox active drug and a third drug with a different mode of action have now been...