HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells

• Main Authors: Yoo-Wook Kwon (Author), Hyo-Suk Ahn (Author), Jin-Woo Lee (Author), Han-Mo Yang (Author), Hyun-Jai Cho (Author), Seok Joong Kim (Author), Shin-Hyae Lee (Author), Heung-Mo Yang (Author), Hyun-Duk Jang (Author), Sung Joo Kim (Author), Hyo-Soo Kim (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although human induced pluripotent stem cells (iPSCs) can serve as a universal cell source for regenerative medicine, the use of iPSCs in clinical applications is limited by prohibitive costs and prolonged generation time. Moreover, allogeneic iPSC transplantation requires preclusion of mismatches b...