Autoimmune Congenital Heart Block: A Review of Biomarkers and Management of Pregnancy

• Main Authors: Sara De Carolis (Author), Cristina Garufi (Author), Ester Garufi (Author), Maria Pia De Carolis (Author), Angela Botta (Author), Sara Tabacco (Author), Silvia Salvi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Autoimmune Congenital Heart Block (CHB) is an immune-mediated disease due to transplacental passage of circulating anti-Ro/SSA and anti-La/SSB autoantibodies. It occurs in 2% of anti-Ro/SSA-exposed pregnancies, and recurrence rate is nine times higher in subsequent pregnancies. Aim of this review is...