Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review
Abstract Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophys...
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| Auteurs principaux: | , , , |
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| Format: | Livre |
| Publié: |
Sociedade Brasileira de Dermatologia,
2016-06-01T00:00:00Z.
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| Résumé: | Abstract Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, clinical features, prevention and treatment of cutaneous graft-versus-host disease. We discuss various insights into the disease's mechanisms and the different treatments for acute and chronic skin graft-versus-host disease. |
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| Description: | 0365-0596 10.1590/abd1806-4841.20164180 |