In vitro intestinal permeability studies, pharmacokinetics and tissue distribution of 6-methylcoumarin after oral and intraperitoneal administration in Wistar rats

In vitro intestinal permeability studies, pharmacokinetics and tissue distribution of 6-methylcoumarin after oral and intraperitoneal administration in Wistar rats

ABSTRACT 6-Methylcoumarin (6MC) is a semisynthetic coumarin with important in vitro and in vivo anti-inflammatory activity. In order to continue the pre-clinical characterization of this molecule, in vitro intestinal permeability, plasma profile and tissue distribution after oral administration in r...

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Main Authors: Paola Andrea Cárdenas (Author), Jadel Müller Kratz (Author), Aura Hernández (Author), Geison Modesti Costa (Author), Luis Fernando Ospina (Author), Yolima Baena (Author), Cláudia Maria Oliveira Simões (Author), Álvaro Jimenez-Kairuz (Author), Marcela Aragon (Author)
Format: Book
Published: Universidade de São Paulo, 2017-04-01T00:00:00Z.
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