Assembly of Celastrol to Zeolitic Imidazolate Framework-8 by Coordination as a Novel Drug Delivery Strategy for Cancer Therapy

• Main Authors: Na Wang (Author), Yifan Li (Author), Fei He (Author), Susu Liu (Author), Yuan Liu (Author), Jinting Peng (Author), Jiahui Liu (Author), Changyuan Yu (Author), Shihui Wang (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Celastrol (Cel), a compound derived from traditional Chinese medicine <i>Tripterygium wilfordii Hook.</i> F, has attracted considerable attention as an anticancer drug. However, its clinical application is limited due to its low bioavailability and potential toxicity. With the advancemen...