KAS-seq profiling captures transcription dynamics during oocyte maturation

• Main Authors: Huiqing An (Author), Xiuwan Wang (Author), Jiashuo Li (Author), Hongzheng Sun (Author), Shuai Zhu (Author), Juan Ge (Author), Longsen Han (Author), Bin Shen (Author), Qiang Wang (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract In fully grown oocytes, the genome is considered to be globally transcriptionally silenced. However, this conclusion is primarily derived from the results obtained through immunofluorescence staining or inferred from the highly condensed state of chromosomes, lacking more direct evidence. H...