Inhalative IL-10 Attenuates Pulmonary Inflammation following Hemorrhagic Shock without Major Alterations of the Systemic Inflammatory Response

• Glavni autori: Philipp Kobbe (Autor), Philipp Lichte (Autor), Helen Schreiber (Autor), Lucy Kathleen Reiss (Autor), Stefan Uhlig (Autor), Hans-Christoph Pape (Autor), Roman Pfeifer (Autor)
• Format: Knjiga
• Izdano: Hindawi Limited, 2012-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Several studies report immunomodulatory effects of endogenous IL-10 after trauma. The present study investigates the effect of inhalative IL-10 administration on systemic and pulmonary inflammation in hemorrhagic shock. Male C57/BL6 mice (8 animals per group) were subjected to pressure-controlled he...